Possibly related posts: (automatically generated)
Purpose of BlogFriday, May 20, 2011
Definition: alpha-1 antitrypsin deficiency | Journal of Online Hepatology
Alpha-1 antitrypsin deficiency is an inherited disorder of protein folding that occurs inside hepatocytes, such that the dysfunctional protein accumulates and leads to chronic inflammation and scar. Since the a-1AT protein is not sufficiently exported to the lung, it cannot protect against proteolytic degration of elastin (and leads to periacinar emphysema).
Subscribe to:
Post Comments (Atom)
0 comments:
Post a Comment